Waters 600e - Page 143

118 Troubleshooting
Figure 6-3 Erratic System Pressure Troubleshooting
Erratic System Pressure
Instrument Problem. Call
Waters Technical Service.
Is the Transducer
Operating Properly?
No
No
Yes
No
Is the Pump Operating
Properly?
Are You Running a
Gradient?
Is Mobile Phase Properly
Sparged and Degassed?
Are Miscible Eluents Being
Used?
Are You Using Volatile
Eluents (Such as Ethers)?
Set Flow Rate to 0. Is
Pressure Stable?
Defective Transducer. Call
Waters Technical Service.
No
No
Prime the Pump (See 600E Multisolvent
Delivery System User’s Guide,
Chapter 3). Is Pressure Still Erratic?
Pump Problem.
See Section 6.3.
No
Yes
Yes
Yes
No
Yes
Do Pressure Changes
Reproducibly Follow the
Gradient Changes?
No
Pressure Fluctuations Are
Normal Due to Viscosity
Changes Between Eluents.
No
No
Pump Problem. See
Section 6.3.
Yes
Yes
Yes
Yes
Degas/Helium Sparge
Eluent.
Are Both Pump Heads
Working? Place Finger on
Indicatior Rod.
Check Eluent Misciblity (See 600E Multisolvent
Delivery System User’s Guide, Appendix B).
Change Eluents if Necessary.
Degas/Helium Sparge
Eluent.