Celite ACT - 6 Art: 714185-00N Rev. Date: 30-Jan-12
Performance of the i-STAT Celite ACT at lower levels of heparin is shown below with two “Low Range” ACT
methods included for comparison:
Medtronic LR-ACT, s
Test Limitations
The i-STAT
Celite
ACT test is to be used with fresh venous or arterial whole blood samples. The presence
of exogenously added heparin, citrate, oxalate, or EDTA will interfere with test results. Poor technique in
sample collection may also compromise the results. Samples drawn from insufficiently flushed catheters
or from traumatic venipunctures may be contaminated with interfering substances. Samples should be
collected into plastic syringes or tubes. Collection into glass may prematurely activate coagulation resulting
in accelerated clotting times.
The i-STAT ACT test uses Celite brand diatomaceous earth as the activator of the intrinsic pathway. The
result may, therefore, be prolonged in the presence of aprotinin.
4
The test is not recommended for use
with patients receiving aprotinin.
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