PROPRIETARY INFORMATION
CONFIDENTIAL MATERIAL
Not for Customer Distribution Assays/Reagents
AEROSET
®
System Troubleshooting Guide 89
94816-107—November 2004
Therapeutic Drug Monitoring (TDM) Assays
The Abbott Clinical Chemistry Therapeutic Drug Monitoring
(TDM) menu includes Carbamazepine, Phenobarbital,
Phenytoin, and Theophylline.
Calibration
• A full calibration is required with each reagent cartridge
change and each change in reagent lot number.
• CAL 1 must always be used as the blank. Do not use water
to calibrate.
• A Blank Adjustment calibration using CAL 1 is required
once each day of assay use, unless a full calibration is
performed.
• To obtain recommended volume requirements for the
Abbott TDM calibrators, hold the bottles vertically and
dispense two drops (50 µL) of each calibrator into each
respective sample cup.
Troubleshooting Tips
The following issues may impact TDM assay results:
•Crimped tubing
• Flared tubing—reagent probes
• Wash flow rates for reagent and sample probes
• Cuvette dryer tip tubing disconnected
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