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Abbott AEROSET - Assay Characteristics; Instrument Troubleshooting

Abbott AEROSET
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PROPRIETARY INFORMATION
CONFIDENTIAL MATERIAL
Flowcharts Not for Customer Distribution
248
AEROSET
®
System Troubleshooting Guide
94816-107—November 2004
Abbott Assay—Basic Assay Troubleshooting, Continued
Assay Characteristics
If multiple assays are affected, look for similar characteristics
such as:
Same line
Assays using R1 only vs. assays using R1 and R2
Similar wavelengths
Same calibrators
Same sample and reagent volumes
Rate vs. end-point reaction
If the issue affects one assay:
Verify assay parameters with the assay-specific package
insert
Was a different bottle of reagent, calibrator, or control
used, and was it handled correctly?
Was a different lot of calibrator or reagent used?
Are there any non-Abbott assays on the original line? If so,
were carryover studies performed between those assays
and the affected assay?
Move the assay to an alternate line. If the issue is not
resolved, proceed to step 2 of Instrument
Troubleshooting.
Instrument Troubleshooting
1. Is the issue on both lines? If yes, troubleshoot common
items, including:
•Lamp
Cuvette washer
•Water
Bulk solution use
•Maintenance
•Probe/mixer wash flow

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