Page 32 VK 7025 Dissolution Apparatus Revision H, 11/10
Setup Operator’s Manual P/N 70-9033
Varian, Inc.
Step 3. Press and hold DRIVE DOWN until the drive unit is at its lowest position.
Step 4. Using a height gauge tool (optional), gently press down the rotating
cylinder shaft to set the height to the USP-specified height of 25 ± 2 mm
above the bottom of the vessel.
Step 5. Place a shaft locking ring on the top of the shaft and slide it down until it
rests on the shaft collar.
Step 6. Rotate the shaft locking ring so the drive positioning teeth on both the
shaft locking ring and the shaft collar rest against one another, locking
the shaft in place.
Step 7. Tighten the set screw using the 7/64-inch T-handle Allen wrench
provided.
Step 8. Repeat steps 3 - 7 for each of the remaining positions.
Step 9. Lower the drive unit until it stops. The rotating cylinders are set at the
USP-specified height of 25 ± 2 mm above the bottom of the vessel.
Installing the Intrinsic Dissolution Apparatus
Step 1. Raise the drive unit to its home position.
Step 2. Carefully insert an intrinsic dissolution apparatus shaft into a spindle until
approximately half of the shaft is above the top of the spindle.
Note
There is a safety mechanism in the bottom of the left side guide
rod which keeps the drive unit from lowering improperly. If the
rods do not line up precisely with the holes in the vessel plate,
the mechanism engages and the drive unit stops lowering and
rises to the home position. See Figure 4, “Drive Unit Guide
Rods,” on page 24.
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