25
2.4.2 Connecting the Sample Line
1. Connect the sample line to the Multi-Channel Online Monitor manifold connector (Figure 2-13). Ensure that
sample line is connected to the correct vessel input connector, and that the connection is securely fastened.
2.5 Fluid Path Sterility Considerations
The Multi-Channel Online Monitor will maintain sterility from the vessel to the monitor sample cup. Additionally, the FISP
sampling probe, which houses a 0.2 um membrane, provides a sterile barrier for the vessel. To better assure fluid path
sterility, the following aseptic techniques are provided.
2.5.1 Autoclaved Vessels
1. Once the vessels have been autoclaved and have cooled to room temperature remove the Vessel 1 sample tubing
from the polypropylene package.
2. Spray the Vessel 1 sample line connectors with 70% ethanol or IPA.
3. Remove the sample line disc filter and fasten Vessel 1’s sample line to the Multi-Channel Online Monitor Vessel 1
connector.
4. Repeat steps 1 through 3 for each successive vessel.
2.5.2 SIP Vessels
1. Connect the sample tubing to the D-Series FISP probes in the same manner used for the autoclaved vessels.
2. Autoclave the D-Series FISP probes and sample tubing assemblies.
3. Once the FISP probes have been autoclaved, allow them to cool to room temperature.
4. Remove the FISP probe/sample tubing assembly from the autoclave bag.
5. Insert each FISP probe into its respective Ingold vessel port. Ensure the sample valve is in the closed position and
the probe is securely fastened with the retainer nut prior to sterilization.
6. SIP each vessel per local protocols.
7. Allow the vessel to cool to the prescribed operating temperature
8. Remove the tubing from the polypropylene package.
9. Spray the Multi-Channel Online Monitor sample line connectors with 70% ethanol or IPA.
To Next Page
Loading...
