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Advanced Instruments OsmoPRO - Known Limitations

Advanced Instruments OsmoPRO
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10
The OsmoPRO
®
Micro-Osmometer Service Manual
1Performance at Reference Conditions: 20 °C to 25 °C (68 °F to 77 °F); 40 to 60 % relative humidity; tolerances
of reference or calibration solutions excluded.
2
Operating Conditions: Temperature 18 °C to 35 °C (64 °F to 95 °F); 30% to 80 % relative humidity (non-condens-
ing).
Known Limitations
Additives such as anti-coagulants from collection tubes may contribute to the measured
osmolality.
Particulate matter can cause premature crystallization, i.e. sample pre-freeze. The particulate
matter may be eliminated in blood and urine by centrifugation. It may also be eliminated in
urine by filtration.
Samples with air bubbles do not reliably freeze and may yield inaccurate results.
Samples allowed to evaporate will yield higher osmolality values.
Non-aqueous solutions will not yield accurate results. The OsmoPRO is intended to test
aqueous solutions only.
Highly viscous solutions may not reliably freeze and may yield inaccurate results.
High concentrations of ethanol, acetone, methanol, isopropanol, ethylene glycol, diethyl
ether, paraldehyde, trichloroethane, or propylene glycol may not reliably freeze and may
yield inaccurate results.

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