Agilent Technologies 1260 Infinity User Manual

88 1260 Infinity Binary Pump User Manual
5 Optimizing Performance
How to Optimize the Compressibility Compensation Setting
Optimization of Legacy Compressibility Settings
The compressibility compensation default settings are 50 × 10
-6
/bar (best
for most aqueous solutions) for pump head A and 115 × 10
-6
/bar (to suit
organic solvents) for pump head B. The settings represent average values
for aqueous solvents (A side) and organic solvents (B side). Therefore it is
always recommended to use the aqueous solvent on the A side of the
pump and the organic solvent on the B side. Under normal conditions, the
default settings reduce the pressure pulsation to below 2 % of system
pressure, which is sufficient for most applications. If the compressibility
values for the solvents used differ from the default settings, it is
recommended to change the compressibility values accordingly.
Compressibility settings can be optimized by using the values for various
solvents described in Table 8 on page 89. If the solvent in use is not listed
in the compressibility table, when using premixed solvents and if the
default settings are not sufficient for your application, the following
procedure can be used to optimize the compressibility settings:
1 Start channel A of the binary pump with the required flow rate.
2 Before starting the optimization procedure, the flow must be stable. Use
degassed solvent only. Check the tightness of the system with the
pressure test (see “(System) Pressure Test” on page 126).
3 Your pump must be connected to an Agilent data system or Instant
Pilot, the pressure- and %- ripple can be monitored with one of these
instruments, otherwise connect a signal cable between the pressure
output of the isocratic pump and a recording device (for example, 339X
integrator) and set following parameters.
Zero 50 % Att 2^3 Chart Speed 10 cm/min
4 Start the recording device in plot mode.
5 Starting with a compressibility setting of 40 × 10
-6
/bar, increase the
value in steps of 10. Re- zero the integrator as required. The
compressibility compensation setting that generates the smallest
pressure ripple is the optimum value for your solvent composition.
6 Repeat step 1 through step 5 for the B channel of your binary pump.

Agilent Technologies 1260 Infinity Specifications

General

Brand	Agilent Technologies
Model	1260 Infinity
Category	Laboratory Equipment
Language	English