Roche Diagnostics
Operatorโs Manual ยท Version 3.4 C-25
Cedex Bio analyzer 8 Data analysis methods
Photometric measurements
Corrections
Volume correction after dilution Volume correction after dilution is carried out with quantitative analysis for
calibrations, controls and samples.
The calculation of the results may require correction (for example due to dilution) or
additional calculations. Various checks will then be carried out.
If a control sample has been diluted the corresponding correction factor is applied.
For calibrations, controls and samples in general the results are determined
according to the following equation:
For diluted samples:
The โจ flag is displayed if is used.
Compensation correction Compensation correction is carried out after every result calculation. In this way,
results can be adapted to other methods.
With the compensation offset, additive corrections on the result can be made. These
corrections have to be verified experimentally.
Correlation correction Carried out after every result calculation. In this way, results of different analyzers in
the same lab can be correlated.
The correlation factor and offset are the slope and y-intercept, respectively, of the
straight line obtained. These values must be determined experimentally.
Results with dilution correction of controls or samples in standard
units.
Results after calculation of controls or samples in standard units.
Sample postdilution factor.
Sample predilution factor.
CV
samp-n
CC
samp-n
F
pred
โ
=
CV
samp-n
CC
samp-n
F
pred
F
postd
โ
โ
=
Results of controls or samples.
Results (including dilution correction) of controls or samples.
Compensation offset.
Correlated result of controls or samples in standard units.
Results (including dilution correction) of controls, or samples.
Lab correlation factor (test parameter).
Lab correlation offset (test parameter).
C
samp-n
CV
samp-n
F
corr
โ
()O
corr
+=