Table of Contents xi
Copyright notice ................................................................................................... ii
Trademarks ............................................................................................................ ii
Customer comments ............................................................................................ iii
Contacting Waters ............................................................................................... iii
Safety considerations .......................................................................................... iv
Considerations specific to the TQ Detector ....................................................... iv
Safety advisories................................................................................................. vi
Operating this instrument ................................................................................ vii
Applicable symbols ........................................................................................... vii
Intended use...................................................................................................... vii
Calibrating ........................................................................................................ vii
Quality control ................................................................................................. viii
ISM classification ................................................................................................. ix
EC authorized representative ........................................................................... ix
1 Waters TQ Detector ............................................................................... 1-1
Overview ............................................................................................................. 1-2
Waters TQ Detector......................................................................................... 1-2
ACQUITY TQD UPLC/MS system ................................................................. 1-4
Software and data system ............................................................................... 1-5
ACQUITY UPLC Console................................................................................ 1-6
Ionization techniques and source probes ................................................... 1-7
Electrospray ionization (ESI).......................................................................... 1-7
Combined ESI and APCI (ESCi)..................................................................... 1-7
Atmospheric pressure chemical ionization..................................................... 1-8
Atmospheric pressure photoionization ........................................................... 1-8
Ion optics ............................................................................................................. 1-9
Table of Contents