Chapter 1 Before Use
HA-8180V 1-2
1.1 Overview
1.1.1 Main Functions
The HA-8180V measures HbA1C glycated hemoglobin and provides information necessary for controlling blood
glucose in diabetics. It can measure stable HbA1
C (S-A1C, HbA1C) and HbF. Measurements made with the HA-8180V
are accurate because labile HbA1
C (L-A1C), carbamylated Hb and acetylated Hb are eluted separately from stable
HbA1
C peak.
Sample measurement
The instrument can measure hemolysis samples that have been diluted with CONTROL DILUTION SET 80 as well
as whole blood samples.
Two measurement modes, Variant and Fast: In addition to measuring HbA1
C and HbF, this instrument can
detect variant Hb, HbS and HbC, in the Variant mode. If HbS and HbC detection is unnecessary, setting the Fast
mode shortens measurement time.
Sample measurements can be performed in the following two ways:
Normal measurement
Normal measurement continuously measures multiple samples using sample racks. One sample rack can hold up to
10 samples. Load the sample racks with samples onto the sampler and press . The instrument then automatically
moves the racks and measures the samples sequentially.
For anemia sample: A special rack is supplied to measure whole blood samples from patients previously
diagnosed as anemic. Samples on the anemia rack are measured at a lower dilution ratio than samples on the normal
racks. This avoids abnormal low value errors to occur.
STAT measurement
You can measure a single sample by setting it in the STAT port. This allows you to interrupt normal measurement in
an emergency to perform a measurement.
HbA1C control measurement
Control measurements should be carried out at regular intervals to check the accuracy of measurement results. Use
commercially available controls that are specified by your distributor.
HbA1C calibration
Periodically calibrating the instrument can eliminate measurement errors caused by changes in environmental
conditions. Calibration can be performed in the following two ways:
Automatic calibration
Calibration coefficients (operation coefficients) for correcting measurement results are automatically calculated by
measuring two standard solutions.
Calibration coefficient setting
You can enter calibration coefficients using the numeric buttons on the operator panel.
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