Why do I see fatty tissue collapse in blocks & microsections with Milestone LOGOS One?
If you observe fatty tissue collapse in blocks and microsections, it might be due to inadequate tissue fixation reacting with JFC, or the absence of connective tissue parenchyma. To address this, fix the tissue conventionally overnight or include heated fixation. Alternatively, use the JFC followed by Isopropanol protocol for processing.
What to do if there is incomplete clearing of fat in Milestone LOGOS One?
Incomplete clearing of fat can occur if the processing cycle is too short or if isopropanol is inefficient for fat clearing, or if the dehydration/clearing agent reuse life has been exceeded. Using an appropriate size processing cycle or reducing the tissue block thickness may help. As an alternative clearing agent, use JFC, or replace the dehydration or clearing reagent.
Why are there pigment deposits in sections when using Milestone LOGOS One?
Pigment deposits in sections may arise from incomplete fixation of blood. Perform a pigment test to determine if they are formalin pigment or hemosiderin deposits. Consider including heated fixation or extending conventional fixation time to improve fixation.
What to do if specimens detach from surrounding WAX in Milestone LOGOS One Laboratory Equipment?
Specimens detaching from the surrounding wax may be due to a processing cycle that is too short. Try using an appropriate size processing cycle or reducing the tissue block thickness.
How to fix white appearance of block face with Milestone LOGOS One Laboratory Equipment?
A white appearance of the block face indicates that wax infiltration is not entirely complete. To resolve this, increase the wax infiltration time.
What causes collapse of block face after sectioning with Milestone Laboratory Equipment?
Collapse of the block face after sectioning suggests that wax infiltration is not entirely complete. Increasing the wax infiltration time should resolve this issue.
How to resolve poor dehydration in Milestone Laboratory Equipment?
Poor dehydration can be caused by alcohol contamination (water), the use of sponge pads or inefficient biopsy pads, or a processing cycle that is too short. Replace the alcohol, extend the processing time, use sponge alternatives or use appropriate size processing cycle to resolve this.
What causes pyknotic nuclei and severe cytoplasmic distortion in Milestone Laboratory Equipment?
Pyknotic nuclei and severe cytoplasmic distortion can result from poor fixation. Extend the fixation time, or use the JFC/Isopropanol program to address poor fixation or JFC reaction issues.
Explains warning and informational symbols used throughout the manual.
Physical space, power, and electrical connection guidelines.
How to start and manage various processing modes.
Managing reagent expiration, cycles, and usage limits.
Step-by-step guide for replacing reagents and wax.
How the system behaves during power interruptions.
Common problems and solutions for tissue processing.
General| Brand | Milestone |
|---|---|
| Model | LOGOS One |
| Category | Laboratory Equipment |
| Language | English |
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