Waters SYNAPT G2 - Page 12

xii Table of Contents
Instrument sources ........................................................................................... 1-5
LockSpray source and ionization modes......................................................... 1-5
NanoLockSpray source.................................................................................... 1-7
Dual-mode ionization source........................................................................... 1-9
Matrix-assisted laser desorption ionization ................................................... 1-9
IntelliStart Fluidics system ............................................................................ 1-9
Overview........................................................................................................... 1-9
IntelliStart Fluidics physical layout............................................................. 1-10
System operation ........................................................................................... 1-11
Ion optics ........................................................................................................... 1-12
Analyzers ........................................................................................................... 1-13
Quadrupole..................................................................................................... 1-13
Triwave technology........................................................................................ 1-14
TOF analyzer ................................................................................................. 1-15
Mass spectrometer configuration ............................................................... 1-17
Triwave device ............................................................................................... 1-17
TOF................................................................................................................. 1-17
Leak sensors ..................................................................................................... 1-18
Vacuum system ................................................................................................ 1-18
Controls on the instrument’s rear panel ................................................... 1-19
2 Starting Up and Shutting Down the Mass Spectrometer ............. 2-1
Starting the mass spectrometer .................................................................... 2-2
Calibration information................................................................................... 2-3
Flow rates for the ACQUITY UPLC SYNAPT G2 MS
UPLC/MS/MS system................................................................................ 2-3
Preparing the IntelliStart Fluidics system ................................................. 2-4
Installing the vials........................................................................................... 2-4
Purging the pump ............................................................................................ 2-5
Shutting down the mass spectrometer ........................................................ 2-6
Putting the mass spectrometer in Standby mode .......................................... 2-6
Fully shutting down the mass spectrometer.................................................. 2-6