411829-L, Description and Specifications April 2012 Page 1-19
1
1.3.3 Solvent Specifications
WARNING
Many solvents are considered to be hazardous to humans and the
environment, so take appropriate safety precautions when using them.
Comply with Material Safety Data Sheets (MSDS) and any other applicable
regulations for the safe use, handling, transporting, storage, and disposal
of these solvents.
1
Neue U. D. HPLC Columns Theory, Technology, and Practice, Wiley-VCH (1997).
2
Dean J. A. Lange’s Handbook of Chemistry, 15
th
edition, McGraw-Hill (1999).
3
Snyder L. R. and Kirkland J. J. Introduction to Modern Liquid Chromatography, Wiley (1979).
Solvent CAS No. EC No.
Strength
1,2
Selectivity
Class
3
UV Cutoff
(nm)
Vapor
Pressure at
20°C (psi)
Vapor
Pressure at
20°C (mbar)
Acetone 67-64-1 200-662-2 0.56 6 (VIa) 330 3.6 247.4
Acetonitrile 75-05-8 200-835-2 0.65 6 (VIb) 190 1.4 93.6
Cyclohexane 110-82-7 203-806-2 0.04 0 210 1.5 103.4
Dichloromethane
(Methylene chloride)
75-09-2 200-838-9 0.42 5 (V) 235 6.9 475.3
Ethanol 64-17-5 200-578-6 0.88 2 (II) 210 1.3 90.0
Ethyl acetate 141-78-6 205-500-4 0.58 6 (VIa) 255 1.4 98.3
n-Heptane 142-82-5 205-563-8 0.01 0 210 0.7 47.4
n-Hexane 110-54-3 203-777-6 0.01 0 210 2.3 161.6
Methanol 67-56-1 200-659-6 0.95 2 (II) 210 1.9 129.7
2-Propanol 67-63-0 200-661-7 0.82 2 (II) 210 0.6 44.0
Tetrahydrofuran 109-99-9 203-726-8 0.57 3 (III) 220 2.5 172.4
Toluene 108-88-3 203-625-9 0.29 7 (VII) 286 0.4 29.1
Water 7732-18-5 231-791-2 1.00 0 190 0.3 23.4