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Biotage Isolera Four - Chapter 6 Troubleshooting

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411829-L, Troubleshooting April 2012 Page 6-1
Chapter
6
Troubleshooting
WARNING
Before performing any procedures in this chapter, please read and observe
the safety requirements in the “Isolera Installation and Safety” document
(P/N 411828). Failure to follow those requirements may result in personal
injury and/or equipment damage. If the system has been damaged and
does not function properly, shut it down and contact Biotage 1-Point
Support immediately.
6.1 Contact Biotage 1-Point Support
If your problem persists, or for assistance at any time during troubleshooting, contact Biotage
1-Point Support. See contact details on page 7-1.
6.2 Accessories and Spare Parts
A condensed list of accessories is available on page 5-1. For a complete list, please contact you
local representative.
A list of spare parts is available at www.biotage.com.
6.3 Fraction Collector-Related Problems
Problem Possible Causes Solutions
1. The collection arm
does not position
correctly over each
collection vessel.
a. Misaligned rack(s). Ensure that the rack(s) is/are aligned correctly.
b. Wrong rack type
selected in the
software.
Ensure that you select the correct rack type when
setting up a method; see “Create, Open, and Edit
Methods” on page 4-2.
c. Incorrect rack
parameters. (Only if
using a user-defined
rack type.)
Ensure that the correct rack parameters have been
entered for the used rack type; see “Administrate
the Rack List” on page 2-5.
d. The collection arm is
obstructed.
Remove any obstacles that obstruct or restrict arm
movement.
e. Improper calibration
of the collection arm.
Calibrate the collection arm; see “Calibrate the
Fraction Collector” on page 3-13.
2. Dripping needle
and/or inconsistent
dispensing
volumes
.
Dirty collect valve.
Clean the collect valve with methanol or a similar
solvent using the Collect Valve Clean Wizard; see
page 3-13.

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