Getinge Maquet FLOW-i 4.2

6.15.3 MAC values
The presented MAC (MAC
rel,barcomp
) is relative
to MAC
40
, and pressure compensated to
account for fluctuations in ambient pressure.
It is calculated as follows:
MAC*10
O%N
MAC*10
%Agent2
MAC*10
%Agent1
MAC
ON
40))*(age0.00269(
2
Agent2
40))*(age0.00269(
Agent1
40))*(age0.00269(
rel
2
+
+=
−−
−−
−−
and,
1013mbar
P
*MACMAC
amb
relbarcomprel,
=
where,
• %Agent1 is the end-tidal concentration of
primary agent.
• MAC
Agent1
is the MAC value for the primary
agent in percent of 1 atm.
• %Agent2 is the end-tidal concentration of
the secondary agent.
• MAC
Agent2
is the MAC value for the
secondary agent in percent of 1 atm.
• %N
2
O is the end-tidal concentration of N
2
O.
• MAC
N2O
is the MAC value for N
2
O in
percent of 1 atm.
MAC
Agent
is a constant related to the delivered
anesthetic agent:
MAC
40
Agent and N
2
O
1.15%Isoflurane (Forene)
2.1%Sevoflurane (Sevorane)
6.6%Desflurane (Suprane)
105 % (=MAC
N2O
)N
2
0 (Nitrous Oxide)
The above values are based on the anesthetic
requirements of a test group comprised of
healthy males, age 40, i.e. MAC
40
.
The presented MAC is the sum of the
individual MAC
rel,barcomp
values for all detected
anesthetic agents and N
2
O.
The equation compensates for the age
difference, as defined by the current patient
case settings, between the patient and the
'MAC
40
' reference group. If the set age is
below 1 or above 80, '1' or '80' will be used
to calculate the MAC
rel
respectively.
FLOW-i 4.2, User's Manual
145
| Breathing system |
6 |