OPTIMedical OPTI CCA-TS - Page 197

Operator’s Manual – OPTI CCA-TS PO2-3
ANALYTES PO
2
Linearity
4
Wherever possible, linearity for the OPTI CCA measurement has been established against reference
materials or methods. PO
2
linearity is established against values determined on whole blood tonometered
to gravimetrically prepared gases with O
2
concentrations certied to 0.03% absolute by the manufacturer,
and measured on three OPTI CCA systems.
Correlation
 Slope Intercept Coefcient Sy.x  Range  n
0.9844 1.864 0.99974 4.52 21 – 500 68
Correlation to Other Methods
4
OPTICCAvsotherpH/BloodGasInstrumentsonwholebloodinatypicalsetting
Excess blood aliquots from specimens collected for blood gas analyses were analyzed by both traditional
and non-traditional operators of blood gas equipment in hospital laboratories. The blood was analyzed on
the OPTI CCA after obtaining the requisite results from existing instrumentation used for these analyses
and operated and controlled following their established procedures.
Correlation
ComparativeMethod* Slope Intercept Coefcient Sy.x Range n
Analyzer A (whole blood) 0.9419 3.28 0.9875 18.27 36 - 563 103
Analyzer B (whole blood) 1.0192 -4.13 0.9969 4.10 34 - 291 173
Analyzer C (whole blood) 0.918 ± 0.087 8.083 ± 1.402 0.9954 8.032 29 – 407 105
Analyzer D (whole blood) 1.041 ± 0.006 -6.244 ± 0.931 0.9969 6.379 37 – 598 174
Analyzer E (whole blood) 0.993 ± 0.009 1.646 ± 0.893 0.9925 4.458 34 – 321 183
* For more information on specic analyzers used, please contact OPTI Medical Technical Support.
References
1. Tietz, Norbert W., Ed., Clinical Guide to Laboratory Tests, 2nd Ed., (Philadelphia: W.B.Saunders,
Co., 1990) p. 436
.
2. Kautsky H, Quenching of Luminescence by Oxygen, Transactions Faraday Society 35, p.216, 1939
3. CDI, 3M Healthcare System 200 Extracorporeal Blood Gas Monitor. See, for example, Lubbers DW,
Gehrich J, Opitz N, Fiber Optics Coupled Flourescence Sensors for Continuous Monitoring of Blood
Gases in the Extracorporeal Circuit, Life Supports Systems 4, p.94, 1986.
4. OPTI Medical. Model equation for regression statistics is: [results of OPTI Analyzer] = slope(m)
[comparative method results] + intercept(b).