Operator’s Manual – OPTI CCA-TS PCO2-1
PCO
2
Clinical Signicance
1
The PCO
2
value of arterial blood is used to assess how well the body eliminates carbon dioxide, a
by-product of metabolism. A PCO
2
value below the normal range is termed respiratory alkalosis and
indicates hypocapnia, a condition caused by increased alveolar ventilation such as hyperventilation.
An arterial PCO
2
above the normal range is termed respiratory acidosis and indicates hypercapnia, a sign
of ventilatory hypoventilation and failure, resulting from cardiac arrest, chronic obstructive lung disease,
drug overdose, or chronic metabolic acid-base disturbances.
Measurement Principle
The PCO
2
optode measurement principle is based upon placing a pH optode behind an ion-
impermeable membrane
2
, just as conventional PCO
2
blood gas electrodes employ the Severinghaus CO
2
electrode construction. As such, PCO
2
optodes may suffer interference from volatile acids and bases in
blood, just as conventional PCO
2
electrodes.
The PCO
2
partial pressure is inuenced by the local barometric pressure, as dictated by Dalton’s law.
The OPTI CCA-TS incorporates a pressure transducer, which accurately tracks the local barometric
pressure and automatically compensates for it. The OPTI CCA-TS has been factory-calibrated to the
absolute barometric pressure.
Measurement Range
Range Resolution (Low/High) Units
10 to 200 1/0.1 mmHg
Standard Reference Cassette (SRC) Limit Values
LOW NORMAL HIGH Units
70.0 ± 2 40.0 ± 2 20.0 ± 2 mmHg