OPTIMedical OPTI CCA-TS - Page 220

Glu-2 Operator’s Manual – OPTI CCA-TS
GLUCOSE ANALYTES
Measurement Principle
The glucose optode measurement is based on the enzymatic oxidation of glucose.
Glucose + O
2
gluconic acid + H
2
O
2
glucose oxidase
The sensor is constructed of an enzyme layer over an oxygen sensor. As a sample containing glucose
contacts the sensor, the oxidation of the glucose consumes the oxygen locally present in the sensor.
This decrease in oxygen is detected in the same manner (luminescence quenching) as described for the
PO
2
optode. The amount of glucose is determined to be proportional to the rate at which the oxygen is
consumed.
Measurement Range
Range Resolution (Low/High) Units
30 to 400 0.1 mg/dL
(70 to 400 mg/dL for samples with PO
2
levels between 401-700 mmHg)
1.7 to 22 0.01 mmol/L
Standard Reference Cassette (SRC) Limit Values
LOW NORMAL HIGH Units
40.0 ± 4 110.0 ± 4 300.0 ± 4 mg/dL
2.2 ± 0.22 6.1 ± 0.22 16.65 ± 0.22 mmol/L
Interferences
The OPTI CCA-TS Glu sensor does exhibit an interference from oxalate and EDTA at the levels used for
anticoagulants. Heparin salts are therefore the only acceptable anticoagulants. The OPTI CCA-TS Glu
sensor does exhibit an interference from PO
2
levels that exceed 700 mmHg. The Glu sensor corrects for
PO
2
values up to 700 mmHg. Glucose values are suppressed when PO
2
values are > 700 mmHg.