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prohibited without written permission of Bio-Rad Laboratories, Inc.

Excel, Microsoft, PowerPoint, Windows, and Windows Vista are trademarks of Microsoft Corporation.

Adobe and Reader are trademarks of Adobe Systems Incorporated. Cy is a trademark of GE Healthcare

group companies. Fluor and Quasar are trademarks of Biosearch Technologies, Inc. SYBR and Texas

Red are trademarks of Invitrogen Corporation. Bio-Rad Laboratories, Inc. is licensed by Invitrogen

Corporation to sell reagents containing SYBR Green I for use in real-time PCR, for research purposes

only. Other brands or product names are trademarks of their respective holders.

LICENSE NOTICE TO PURCHASER

Bio-Rad Real-time thermal cycler CFX96 or CFX384 is licensed real-time thermal cycler(s) under Applera's United

States Patent No. 6,814,934 B1 for use in research and for all other fields except the fields of human diagnostics and

veterinary diagnostics.

This CFX96 or CFX384 detection module, when combined with a C1000 thermal cycler for which the applicable real-

time thermal cycler royalty fee has been paid, constitutes a real-time thermal cycler licensed under U.S. Patent No.

6,814,934 and corresponding claims in any Canadian counterpart patent thereof owned by Applera Corporation, for

use solely in research and all applied fields except human and veterinary in vitro diagnostics. These license rights

are effective only if this detection module is combined with a Bio-Rad thermal cycler for which the applicable real-

time thermal cycler royalty fee has been paid and not with any other thermal cycler. No rights are conveyed

expressly, by implication or estoppel to any patents on real-time methods, including but not limited to 5' nuclease

assays, or to any patent claiming a reagent or kit. For further information on purchasing license rights, contact the

Director of Licensing at Applied Biosystems, 850 Lincoln Centre Drive, Foster City, California, 94404, USA.

This product is covered by one or more of the following U.S. patents, their foreign counterparts, or their foreign

patents pending, owned by Eppendorf AG: US Patent Nos. 6,767, 512 and 7,074,367. No rights are conveyed

expressly, by implication or estoppel to any patents on PCR methods, or to any patent claiming a reagent or kit

Bio-Rad’s Hard-Shell® plates are covered by one or more of the following U.S. patents, patents pending, or their

foreign counterparts, owned by Eppendorf AG: US Patent Nos. 7,347,977, 6,340,589, 6,528,302 and US application

2007246858, 20080084004, 20030180192 and 20060120927

BIO RAD CFX96 User Manual

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