Agilent InfinityLab LC Series Vialsamplers User Manual 16
1Introduction  
Overview of the Module
Overview of the Module
The Agilent InfinityLab LC Series Vialsampler is designed for use with other 
modules of the Agilent InfinityLab LC Series, 1200 Series, and 1100 Series LC, as 
well as with other LC systems with adequate remote-control capabilities. The 
Vialsampler can be controlled from any computer with a suitable 
chromatography data system (for example, Agilent OpenLab CDS, MassHunter, 
etc.) or via an Agilent local control module (InfinityLab Companion or 1200 
Infinity Series Instant Pilot).
The 1290 Infinity II Vialsampler (G7129B) can be operated at up to 1300 bar. The 
two 1260 Infinity II Vialsampler variants (G7129A and G7129C) are limited to a 
maximum system pressure of 600 and 800
 bar, respectively.
The Vialsampler can accommodate two vial drawers, providing space for up to 
132 samples. The two cartesian vial drawers allow for the use of either 66 × 2
 mL 
or 18 × 6
 mL vials. A pair of classic vial drawers with a numerical vial assignment 
system is also available, each capable of hosting 50 × 2
 mL vials. The classic vial 
drawers are designed to ease method transfer from older Agilent samplers. The 
Vialsampler can also be equipped with an external tray, which can be beneficial 
for automation. The Agilent WalkUp solution fully supports the external tray.
The Vialsampler features a robotic gripper arm for the transport of vials, driven by 
four stepper motors to ensure the highest precision and flexibility for the 
transport movement.
The default configuration of the analytical head and sample loop allows an 
injection range from 0.1
 – 20 μL for the 1290 Infinity II Vialsampler and 
0.1
 – 100 μL for the 1260 Infinity II Vialsamplers. An analytical head with 
extended volume is also available for injection volumes from 0.1
 – 900 μL, and 
can be operated at up to 400
 bar. With the Multidraw Kit, the maximum injection 
volume can even reach 1800
 μL.
The 2-position/6-port injection valve is driven by a high-speed, hybrid stepper 
motor, ensuring smooth switching between the mainpass and bypass positions. 
Thanks to the flow-through design of the Vialsampler, the eluent continuously 
rinses the component parts of the sample introduction system. This, together 
with the automated needle wash function for rinsing the outer surface of the 
needle, ensures the lowest level of carryover for each analysis. For advanced 
delay volume reduction, the injection valve can be programmed to automatically 
switch back to the bypass position when the injection is completed.