BioPAT
®
Trace | Multi Trace Operating Instructions 103
Operation
In order to avoid a too high influence of the
integral gain on the controller at the beginning,
the integral gain can be reset to the preset value
by “Reset controller” at any time. This command
must then be confirmed with “Ok”.
CAUTION
Always reset the controller after filling the
feeding line or with unknown history to avoid
overdose!
Recommended start settings for the PID
Controller:
t For microbial cultures the following settings
can be recommended:
P = 0.1–0.5 (proportional gain). Depending on
the concentration of the feeding solution,
max. pump speed, diameter of the tubing,
reactor volume, etc.,
I = 45 min (integral time),
D= 2 min (derivative time).
t For cell cultures the following settings can be
recommended:
P = 0.01–0.1 (proportional gain). Depending on
the concentration of the feeding solution,
max. pump speed, diameter of the tubing,
reactor volume, etc.,
I = 60 min (integral time),
D = 1 min (derivative time).
t In most cases adjustment of the P-value and
you can let the I-value and D-value at the
recommended level.
t If the feeding is too strong reduce the P-value
or if it is not enough increase the P-value.
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