LUMENIS smart532 - Page 96

Clinical Guide Smart532
™
A-12 UM-1151440EN, Rev. C, May 2016
Table A-2: Recommended clinical treatment parameters in SmartPulse for intended medical
conditions
Indication Power (mW) References (links)
SmartPulse
duration (ms)
SmartPulse
interval
(ms)
Exposure
duration
(sec)
Spot size (
µ
m)
Diabetic
Retinopathy
including
Macular Edema
or Proliferative
Retinopathy
19
1.2 X test burn
CW power
Lavinsky et al 2011
Kwon et al 2014
Laursen et al 2004
Lutrull et al 2005
Nakamura et al 2010
Ohtman et al 2014
Vujosevic et al 2010
0.1
0.2
0.1
0.1
0.3
0.3
0.1
1.9
1.8
1.9
1.9
1.7
1.7
1.9
0.3
0.02
0.1
0.3
0.2
0.3
0.2
125
100
125
125
200
75-125
100
Range:
0.1-0.3
1.7-1.9
0.02-0.3
75-200
Most commonly used value:
0.1
1.9
0.3
125
Proliferative
Diabetic
Retinopathy
(PDR)
20
2.0 X test burn
CW power
Desmettre et al 2006
Luttrull et al 2008
Moorman & Hamilton 1999
0.3
0.3
0.1-0.3
1.7
1.7
1.7-1.9
0.2
0.2
0.1-0.3
125
500
200-500
Range:
0.1-0.3
1.7-1.9
0.1-0.3
125-500
Most commonly used value:
0.3
1.7
0.2
200
Central Serous
Chorio
Retinopathy
(CSCR)
21
2.0 X test burn
CW power
Koss et al 2012
Breukink et al 2015
Bandello et al 2003
0.3
0.1
0.2-0.3
1.7
1.9
1.8-1.9
0.2
0.2
0.2
125
125
200
Range:
0.1-0.3
1.7-1.9
0.2
125-200
Most commonly used value:
0.3
1.7
02
125
Macular Edema
or Proliferative
Retinopathy
associated with
Branch Retinal
Vein Occlusion
(BRVO)
22
2.0 X test burn
CW power
Inagaki et al 2014
Ohkoshi et al 2010
Moorman & Hamilton 1999
Parodi et al 2006
0.3
0.3
0.1-0.3
1.7
1.7
1.7-1.9
0.3
0.2
0.1-0.3
200
125-200
200-500
Range:
0.1-0.3
1.7-1.9
0.1-0.3
125-500
Most commonly used value:
0.3
1.7
0.3
200
19
D. Lavinsky, J.A. Cardillo, L.A.S. Meli, A. Dare, M.E. Farah, and R. Belfort Jr., “Randomized
Clinical Trial Evaluating mETDRS versus Normal or High-Density Micropulse Photocoagulation
for Diabetic Macular Edema” ,
IOVS , vol. 52(7), pp. 4314-23, 2011
20
T.J. Desmettre, S.R. Mordon, D.M. Buzawa, and M.A. Mainster “Micropulse and continuous
wave diode retinal photocoagulation: visible and subvisible lesion parameters” ,
Br J
Ophthalmol
, vol. 90, pp. 709-12, 2006
21
M.J. Koss, I. Berger, F.H. Koch, “Subthreshold diode laser micropulse photocoagulation
versus intravitreal injections of bevacizumab in the treatment of central serous
chorioretinopathy”,
Eye , Vol. 26, pp. 307-14, 2012
22
K. Inagaki, K. Ohkoshi, S. Ohde, G.A. Deshpande, N. Ebihara and A. Murakami,
Subthreshold Micropulse Photocoagulation for Persistent Macular Edema Secondary to Branch
Retinal Vein Occlusion including Best-Corrected Visual Acuity Greater Than 20/40”,
J
Ophthalmol
, Epub 2014, Sep 4, 2014