cytiva NanoAssemblr Ignite - Page 65

Start waste example calculations
Th
e following examples explain how to calculate the value of the Start waste param-
eter using the Ignite start waste table.
Example 1: Two same sized syringes with dilution
For a formulation with two 3 mL syringes and a 5 mL dilution syringe, the Start waste
value is calculated as follows:
Two same size syringes, 3 mL: 0.50
Dilution syringe, 5 mL:
+ 0.35
Recommended start waste: = 0.85
Syringe size (mL)
Values used to calculate St
art waste for same sized
syringes (mL)
Same size syringes Dilution syringe
1 0.3 0.20
3
0.50
0.25
5 0.70
0.35
10 1.10 0.50
20 - 0.65
30 - 0.65
Example 2: Two different sized syringes without dilution
Fo
r a formulation with a 3 mL and a 5 mL syringe, the Start waste value is calculated as
follows:
Smaller syringe, 3 mL: 0.15
Larger syringe, 5 mL:
+ 0.50
Recommended start waste: = 0.65
Syringe size
(m
L)
Values used to calculate Start waste for different sized
syringes (mL)
Smaller syringe Larger syringe Dilution syringe
1 0.10 N/A 0.20
3
0.15
0.35 0.25
5 0.20
0.50
0.35
10 0.30 0.80 0.50
20 - - 0.65
30 - - 0.65
5 Preparation
5.
1 Parameters
5.1.3 Waste parameters
NanoAssemblr Ignite and Ignite+ Operating Instructions NIN1134 AA 65