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HEPA Filter Replacement
The HEPA filters load with particulate as the biosafety cabinet operates. Eventually, the
filters will need to be replaced. Only replace a HEPA filter if you are a qualified and
trained certifier or technician.
The HEPA filters on a biosafety cabinet will be contaminated with biohazardous
material. Always assume the HEPA filter is contaminated, even if you are told the
biosafety cabinet has not been used. For your safety, take all necessary precautions
before opening the filter cover(s), including: gaseous decontamination of the biosafety
cabinet, proper breathing, eye, and skin protection from biohazards.
Type A2 (8, 9, 10-inch sash)
Follow these instructions carefully, and in the order documented. Always remove the
exhaust HEPA filter first. The exhaust filter pan can be damaged if the plenum is raised
with the exhaust HEPA filter in place.
HEPA filters can be awkward to handle, and quite heavy for larger models. Use safe
lifting techniques when removing and replacing the filters. Always use two persons to
remove and replace each HEPA filter.
1. Thoroughly and properly decontaminate the biosafety cabinet.
2. Remove the front dress panel as described earlier in this section under Removal
of External Dress Panels. Unplug the power cord to this biosafety cabinet.
3. Loosen all of the Phillips screws around the perimeter of the blower/plenum
cover. Remove all screws except two along the top edge of the cover. This will
support the cover. The sash stop bracket is held in place by two of the
blower/plenum cover screws. Remove this bracket.
4. Release the damper seal (Figure 12-6) by pulling the outside edge of the seal
towards the bolt at the center, and then push the seal inside the blower/plenum
cover (Figure 12-7).
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