Agilent 6500 Series Q-TOF LC/MS Maintenance Guide 45
Maintenance 2
To check for leaks
To check for leaks
When required When the sensor indicates a leak has occurred.
Tools required • Cloths, clean, lint-free (p/n 05980-60051)
• Cotton swabs (p/n 5080-5400)
• Screwdriver, TORX, T-10 (p/n 8710-1623) 
Parts required None
1 Remove the front cover and top cover from the instrument.
2 Remove the calibrant bottles.
3 Turn off the Spray Chamber nebulizer pressure, drying gas temp, and 
vaporizer temp (for APCI or multimode).
4 Disconnect the nebulizing gas tubing and the LC tubing from the nebulizer.
5 Remove the spray chamber from the instrument.
6 Remove the two screws and remove the cover of the calibrant delivery 
system.
7 Check the catch tray. If you see liquid, the pump has a leak. If no liquid is 
present, the leak sensor may be out of calibration. See the online Help for 
instructions to calibrate the leak sensor. 
8 If a leak occurs during a long unattended run, the liquid from the leak may 
evaporate to give you the impression that no leak exists and the leak sensor 
is out of calibration. Turn the system back on and make sure no leak exists 
before you recalibrate the leak sensor. 
9 Check the selection valve, the waste fitting, the inlet fitting, and the 
calibrant delivery system valves. If you find a leak, correct it and check the 
remaining locations. 
10 Dry the catch tray and leak sensor. 
11 When the catch tray and leak sensor are thoroughly dry, reassemble the 
instrument. 
The spray chamber operates at very high temperatures. Give the spray chamber time 
to cool before proceeding.