106 Agilent 6500 Series Q-TOF LC/MS Maintenance Guide
2Maintenance
To adjust the multimode nebulizer
To adjust the multimode nebulizer
When required When the needle is plugged. Common symptoms of a plugged needle are
increased LC back pressure or off-axis spraying or dripping from the
nebulizer.
Tools required • Adjustment fixture (p/n G1946-20215)
• Gloves, clean
• Pliers, long nose (p/n 7810-0004)
• Wrench 3-mm, open-end (p/n 8710-2699)
• Wrench ¼-inch x 5/16-inch, open-end (p/n 8710-0510)
Parts required Nebulizer needle kit, Electrospray (includes needle, ferrule, and needle holder,
p/n G2427A)
1 Install the nebulizer in the adjustment fixture.
2 Loosen the locknut next to the zero-dead-volume (ZDV) union.
3 Remove the union from the nebulizer.
4 Loosen the locknut of the needle holder.
5 Unscrew the needle holder and pull it out of the nebulizer.
6 Slide the non-tapered end of the needle through the new needle holder from
the narrower side.
Figure 47 Electrospray nebulizer needle in needle holder
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