Agilent 6500 Series Q-TOF LC/MS Maintenance Guide 25
Basic Operation 1
To remove a dual nano ESI source
To remove a dual nano ESI source
1 Put instrument in Standby mode.
2 Remove the reference and LC nanospray needle assembly from the source.
3 Clean both nanospray needles with 100% acetonitrile. You can also use any
solvent that dissolves the last sample run.
4 Disconnect the power cable from the lamp.
5 Open the spray chamber.
6 Remove the spray chamber by lifting it along the axis of its hinges.
7 Remove the capillary cap and drying gas diverter.
8 Install the standard capillary cap and spray shield. For the standard spray
shield, the small drying gas exit hole should be oriented above the main
hole, or entrance to the capillary cap.
Do not touch the top of the dual nanospray source or the capillary cap. They may be
very hot. Let the parts cool before you handle them.
Do not let the sample recrystallize inside the needle, which leads to plugged needles.
Follow the steps above to prevent plugged needles.
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