24 Agilent 6500 Series Q-TOF LC/MS Maintenance Guide
1 Basic Operation
To remove a nano ESI source
To remove a nano ESI source
1 Put instrument in Standby mode.
2 Remove the nanospray needle assembly from the source.
3 Clean the nanospray needle with 100% acetonitrile. You can also use any
solvent that dissolves the last sample run.
4 Disconnect the power cable from the lamp.
5 Open the spray chamber.
6 Remove the spray chamber by lifting it along the axis of its hinges.
7 Remove the capillary cap and drying gas diverter.
8 Install the standard capillary cap.
The spray chamber operates at very high temperatures. Let the spray chamber cool
before you continue.
Do not let the sample recrystallize inside the needle, which leads to plugged needles.
Follow the steps above to prevent plugged needles.
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