Agilent 6500 Series Q-TOF LC/MS Maintenance Guide 57
Maintenance 2
To remove the electrospray nebulizer
To remove the electrospray nebulizer
When required When you need to access the nebulizer for maintenance.
Tools required Gloves, clean
Parts required None
Figure 10 Electrospray nebulizer
1 Shut off the flow of LC solvent.
2 Shut off the flow of nebulizing gas.
3 Slide back the plastic cover from over the nebulizer.
4 Disconnect the LC tubing and nebulizing gas tubing from the nebulizer.
5 Turn the nebulizer counterclockwise until it disengages from the retaining
screws.
6 Gently lift the nebulizer out of the spray chamber.
Recent residue should be soluble in the mobile phase. If you are not sure what mobile
phase was used recently, a mixture of 50% isopropanol and 50% water works well as
a general cleaning solution.
The tip of the nebulizer may be very hot. Allow it to cool before handling it.