104 Agilent 6500 Series Q-TOF LC/MS Maintenance Guide
2Maintenance
To clean the multimode source weekly
To clean the multimode source weekly
The cleaning procedure for cleaning the multimode source weekly is similar to
the daily procedure. The main difference is that the multimode source is
removed from the instrument in the weekly procedure.
When required Weekly if the normal daily cleaning procedure is not sufficient
Tools required • Gloves
• Wash bottle, clean
Parts required • Abrasive paper, 4000 grit (p/n 8660-0827)
• Cloths, clean, lint-free (p/n 05980-60051)
• Cotton swabs (p/n 5080-5400)
• Mobile phase from the current method or clean isopropanol, reagent grade
or better
• Water, reagent-grade or better
1 Remove the multimode source.
2 Fill the spray chamber with clean mobile phase, or with a mixture of
isopropanol and water.
3 Scrub the corona insulator and the interior of the spray chamber with
a clean cotton swab.
4 Empty the spray chamber.
5 Wipe the interior of the spray chamber with a clean, lint-free cloth
Recent residue should be soluble in the mobile phase. If you are not sure what
mobile phase was used recently, a solution of 50% isopropanol and 50% water
works well as a general cleaning solution.
Some mobile phase are hazardous chemicals. Use the degree of caution appropriate
for the mobile phase being used.
Sharp edges can be found inside the spray chamber, such as the separator. Pay
close attention when wiping the interior of the spray chamber.
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