74 Agilent 6500 Series Q-TOF LC/MS Maintenance Guide
2Maintenance
To clean the spray chamber weekly for the ESI with Agilent Jet Stream
To clean the spray chamber weekly for the ESI with Agilent Jet
Stream
When required Weekly or whenever symptoms indicate that contamination exists in the spray
chamber and normal daily cleaning does not correct the problem
Tools required • Abrasive paper, 8000 grit (p/n 8660-0852)
• Cloths, clean, lint-free (p/n 05980-60051)
• Cotton swabs (p/n 5080-5400)
• Gloves, clean
• Isopropanol, reagent grade or better
• Mobile phase, current
• Wash bottle, clean
• Water, reagent-grade or better
Parts required None
1 Turn off the spray chamber.
2 Remove the electrospray nebulizer.
3 Open the spray chamber and remove it from the LC/MS.
4 Fill the spray chamber with clean mobile phase, or with a mixture of
isopropanol and water.
Recent residue should be soluble in the mobile phase. If you are not sure what mobile
phase was used recently, a mixture of 50% isopropanol and 50% water works well as a
general cleaning solution.
The electrospray with Agilent Jet Stream Technology spray chamber operates at
high temperatures. Allow sufficient time to cool down before cleaning.
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