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Agilent Technologies 6500 Series - To Clean the Spray Chamber Daily for the ESI with Agilent Jet Stream

Agilent Technologies 6500 Series
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Agilent 6500 Series Q-TOF LC/MS Maintenance Guide 71
Maintenance 2
To clean the spray chamber daily for the ESI with Agilent Jet Stream
To clean the spray chamber daily for the ESI with Agilent Jet
Stream
When required Daily or at the end of each shift or anytime you suspect carryover
contamination from one sample or analysis to another
Tools required Cloths, clean, lint-free (p/n 05980-60051)
Gloves, clean
Isopropanol, reagent grade or better
Mobile phase, current
Wash bottle, clean
Water, reagent-grade or better
Parts required None
1 Prepare the mobile phase you have been using.
2 Turn off the spray chamber.
3 Remove the nebulizer.
4 Open the spray chamber (Figure 6).
NOTE
Recent residue should be soluble in the mobile phase. If you are not sure what mobile
phase was used recently, use a mixture of 50% isopropanol and 50% water as a general
cleaning solution.
WARNING
The electrospray with Agilent Jet Stream Technology spray chamber operates at
high temperatures. Allow sufficient time to cool down before cleaning.

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