Agilent 6500 Series Q-TOF LC/MS Maintenance Guide 87
Maintenance 2
To clean the APCI spray chamber daily
1 Turn off the spray chamber.
2 Remove the corona needle.
3 Make sure the needle has cooled and then carefully clean it with abrasive
paper.
4 Open the spray chamber.
Figure 34 Opened spray chamber
5 Rinse the interior of the spray chamber with the current mobile phase or
with a mixture of isopropanol and water.
6 Wipe the interior of the spray chamber and the end of the vaporizer with a
clean cloth.
7 Remove the spray shield.
8 Use abrasive paper to gently clean the end of the capillary cap.
9 Dampen a clean cloth and wipe the end of the capillary cap.
• Recent residue should be soluble in the mobile phase. If you are not sure what mobile
phase was used recently, use a mixture of 50% isopropanol and 50% water as a general
cleaning solution.
• Use the weekly cleaning procedure if symptoms of contamination persist, or if the spray
shield or capillary cap shows significant discoloration that cannot be removed by the
regular daily cleaning.
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