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CELL-DYN
®
3200 System Operator’s Manual
9140181H—October 2001
Operating Instructions
Sample Collection and Handling
Section 5
Interfering Substances
The CELL-DYN 3200 has been designed to detect and flag samples that contain
interfering substances. The following list indicates the substances that may
interfere with the listed parameters.
WBC: NRBCs, lytic-resistant RBCs, PLT clumps, cryoglobulin and
cryofibrinogen, fragile WBCs
RBC: Elevated WBC count, increased numbers of giant PLTs, autoagglutination,
in vitro hemolysis
HGB: Elevated WBC count, increased plasma substances (triglycerides,
bilirubin, in vivo hemolysis), lytic-resistant RBCs
MCV: Elevated WBC count, hyperglycemia, in vitro hemolysis, increased
numbers of giant PLTs
PLT: WBC fragments, in vitro hemolysis, microcytic RBCs, cryoglobulins, PLT
clumping, increased numbers of giant PLTs. For a detailed description of
the flags that are generated, refer to Section 3: Principles of Operation;
Subsection: Operational Messages and Data Flagging.
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