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Copyright information and usage restrictions for the publication.
List of registered and unregistered trademarks associated with the product and company.
Information on document subject to change and BioTek's liability for software/equipment.
Records changes made to the document over different revisions.
Describes the primary applications and purposes of the microplate washer.
Details potential hazards and safety precautions for operating the instrument.
Provides essential cautions to prevent damage to the instrument and ensure safe operation.
Details compliance with electromagnetic compatibility standards for emissions and immunity.
Information on compliance with FCC rules for Class A digital devices regarding radio interference.
Details compliance with Canadian regulations for digital apparatus radio emissions.
Outlines safety requirements met by the device from testing laboratories.
Identifies the main components of the 405 LS microplate washer.
Explains the letter scheme used to identify different 405 LS instrument models.
Details compatibility and integration features with the BioStack Microplate Stacker.
Lists all items included in the instrument package.
Describes various accessories for waste and dispense systems.
Lists available optional accessories for the instrument.
Provides detailed physical and environmental specifications of the instrument.
Details performance metrics such as residual volume, dispense precision, and clog detection.
Information on accessing BioTek's support services and resources online.
Instructions for unpacking and inspecting the instrument and accessories for damage.
Steps for removing protective shipping brackets to prepare the instrument for use.
Guidance on preparing the instrument for operation, including environmental conditions.
Instructions for connecting fluid supply and waste systems for optimal operation.
Steps for preparing and connecting the fluid supply bottles and tubing.
Guide for installing LHC software and connecting the instrument to a host computer.
Instructions for safely connecting the instrument to a power source.
Procedures for configuring instrument settings, including for LHC users and vacuum pump.
Steps to verify the washer is operating properly before initial use.
Procedure for running the Verify test on models equipped with Verify™ Technology.
Instructions for safely repacking the instrument for service or shipment.
Overview of controlling the 405 LS via keypad or LHC software.
Guidelines for ensuring optimal performance and preventing problems.
Instructions on how to run predefined protocols for maintenance and qualification.
Details on defining and running custom wash, aspirate, and dispense protocols.
Description of the keypad layout, menus, and soft-key functions.
Procedure for performing a quick wash using the instrument's keypad.
Steps for creating new wash protocols or editing existing ones via the keypad.
How to set plate types and define processing maps for specific assays.
Introduction to using BioTek's Liquid Handling Control (LHC) software.
Guide for configuring instrument settings in the LHC for protocol execution.
Procedure for verifying instrument operation and performing self-checks.
Instructions for configuring utilities related to Verify™ Technology.
Information on operating the 405 LS in conjunction with the BioStack.
Details on performing cell wash assays and related techniques.
Guidance on performing assays using magnetic beads and associated protocols.
Instructions for using the vacuum filtration accessory with filter-bottom plates.
Procedures for adjusting washer settings like manifold and plate carrier configuration.
Tool for determining and setting precise positioning for dispense and aspirate tubes.
Information on supported plate types and processing patterns.
Introduction to preventive maintenance (PM) regimens for the 405 LS.
Provides recommended maintenance tasks, frequency, and onboard programs.
Procedures for daily flushing and rinsing to prevent tube clogging.
Instructions for setting up AutoPrime to keep tubing wet and prevent clogging.
Maintenance procedures for flushing out protein particles and contaminants.
Details on using the Ultrasonic Advantage™ feature for cleaning manifold tubes.
Regular cleaning procedures for instrument components to maintain performance.
Instructions for cleaning and rinsing supply and waste bottles.
Procedure for cleaning the plate carrier, rails, and glide strips.
Guidelines for maintaining Verify™ Technology components for optimal performance.
Instructions for recalibrating the instrument for a new Verify Test Plate.
Procedures for decontaminating the instrument due to biohazard concerns.
Step-by-step instructions for cleaning the instrument's exterior surfaces.
Procedures for flushing and soaking the supply tubing and manifolds with disinfectant.
Steps for preparing the instrument for extended periods of inactivity or shipment.
Information on periodically replacing components to maintain performance.
Describes the three main activities of instrument verification: IQ, OQ, and PQ.
Defines factory-recommended intervals for verification tests.
Steps to verify software information and run a system self-check.
Tests to simulate error conditions for fluid, waste, and plate detection sensors.
Procedure to verify the proper operation of the ultrasonic cleaner.
Overview of recommended routine tests for before first use and monthly checks.
Detailed procedures for dispense precision and evacuation efficiency tests.
Measures variability of dispensed volumes across the manifold.
Measures residual volume per well after aspiration for evacuation efficiency.
Tests the total residual volume after evacuation for vacuum filtration systems.
Procedure to ensure the Verify Technology level sensor meets performance specifications.
Guidelines for error recovery and addressing common performance issues.
Steps to take for initial response and rebooting the system and computer.
Information on finding and interpreting software and system error codes.
Lists potential performance problems and their solutions for startup and operation.
Lists system error codes and their corresponding messages and actions.
Details software error codes related to protocol conflicts and instrument settings.
General warnings about operating the instrument safely.
Precautions related to light conditions and particles affecting instrument performance.
Safety information related to handling liquids and ultrasonic energy.
Specific warnings regarding internal voltage, power rating, and electrical grounding.
General cautions regarding service, spare parts, environmental conditions, and disposal.
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General