Hologic thinprep 2000 - CYTOLYT SOLUTION

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SOLUTIONS

ThinPrep 2000 Processor Operator’s Manual

2.5

CYTOLYT

SOLUTION

CytoLyt Solution is a methanol-based, buffered, preservative solution designed to lyse red blood

cells, prevent protein precipitation, dissolve mucus, and preserve morphology of general cytology

samples. It is intended as a transportation medium and is used in specimen preparation prior to pro-

cessing. It is not intended for complete inactivation of microbes. Chapter 1, “Non-Gynecologic

Sample Preparation”, describes the uses of CytoLyt Solution in detail.

Packaging

Please refer to the Ordering Information in this manual for part numbers and detailed information

regarding the ordering of solutions and supplies for the ThinPrep 2000 system.

• Box of 4 bottles each containing 1 quart (946 mL) of CytoLyt Solution

• A dispensing pump which attaches to the quart bottles to dispense 30 mL of liquid

• Box of 80, 50-mL centrifuge tubes each containing 30 mL (approx. 1 oz.) of CytoLyt Solution

• Box of 50, 120-mL specimen cups each containing 30 mL (approx. 1 oz.) of CytoLyt Solution

Composition

CytoLyt Solution contains methanol and buffer.

Storage Requirements

• Store the containers at 15°C–30°C without cells.

• Cells in CytoLyt Solution are preserved for 8 days at room temperature; however, for best

results, transport specimen to the laboratory immediately for processing. This 8-day preserva-

tion period pertains to samples in a minimum CytoLyt Solution to sample ratio of one part

CytoLyt Solution to three parts sample.

• Storage requirements for quantities of CytoLyt Solution are dependent on local regulations

regarding the size and configuration of your facility. Please refer to the Solution Storage Guide

at the end of this chapter.

Transportation

Make sure the tubes and specimen cups containing CytoLyt Solution are tightly sealed. Align the

mark on the cap with the mark on the vial to prevent leakage.

SECTION

WARNING:

CytoLyt Solution contains buffered methanol. Danger. Poison. Vapor

harmful. May be fatal or cause blindness if swallowed. Cannot be made non-poisonous.

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