CEM liberty - Safety Information; Fume Ventilation; Waste Disposal; System Requirements

Liberty
™
Automated Microwave Peptide Synthesizer
600178 • Revision 5 • October 2009
14
Safety Information
Fume Ventilation
The Liberty operates as a semi-closed system, with minimal venting of any hazardous solvent
fumes through the vent line coming from the Waste Reservoir. The vent line from the Waste
Reservoir must be vented into a proper chemical fume hood or exhaust line no longer than six
feet (6’)/two meters (2 m) from the instrument.
In addition, adequate ventilation should be provided for preparation of reagents and solvents for
use on the system. All solvent bottles and the Waste Reservoir should be placed into proper
secondary containers to minimize the risk of exposure.
Waste Disposal
Waste produced by the Liberty can be hazardous. For detailed information on the safety
requirements for the chemicals used on the Liberty, refer to the appropriate MSDS documents.
Product Removal
When removing tubes containing cleaved peptide in TFA from the Product Manifold following
cleavage, wear suitable protective clothing. These tubes contain a mixture of TFA, DCM, and
peptide. The centrifuge tubes should be capped immediately after removal from the Liberty to
reduce exposure to solvent fumes.
System Requirements
Bench and/or Fume Hood Space
The Liberty should be positioned on the bench such that access to the electrical outlets for the
system is not restricted. The Liberty requires the following space for system components:
Liberty Instrument (Discover Module and Liberty Module):
30” (w) x 24” (d) x 33.5” (h) [76 cm (w) x 61 cm (d) x 85 cm (h)]
(Depth includes 3” (7.62 cm) clearance behind instrument for unimpeded airow at rear fan ducts)
CEM Supplied Controller:
Laptop:
12.5” (w) x 9.9” (d) x 15.5” (h) [32 cm (w) x 25 cm (d) x 39 cm (h)]
(Height includes 14.1” (35.8 cm) display)
Desktop:
Minitower: 7.4” (w) x 17.5” (d) x 16.1” (h) [19 cm (w) x 44.5 cm (d) x 41 cm (h)]
Monitor: 16” (h) x 8” (d) x 20” (h) [41 cm (h) x 20 cm (w) 51 cm (h)]
External Reagent Bottles:
16” (w) x 16” (d) x 15” (h) [41 cm (w) x 41 cm (d) x 38 cm (h)]
(Left side of instrument, facing front of instrument)
WARNING
Handle all waste under a fume hood, and wear suitable protective clothing.
Dispose of all waste in accordance with all applicable local, state, and
federal health and safety recommendations.