CEM liberty - Section 4: Mainteance of the Liberty; Routine Maintenance; Daily Maintenance; Weekly Maintenance

Liberty
™
Automated Microwave Peptide Synthesizer
600178 • Revision 5 • October 2009
61
Section 4: Mainteance of the
Liberty
Routine Maintenance
A routine maintenance protocol is vital for the long-term operation of the Liberty. Further details
about the maintenance procedures can be found in the Liberty Maintenance Procedures Manual
(PN 600119). The Liberty Maintenance Procedures Manual also contains twelve months of
maintenance logs for recording and maintaining maintenance records.
Daily Maintenance
Inspect the instrument for any visible signs of leakage in all spill trays, any at •
areas inside the Liberty, and inside the cavity of the Discover.
Clean the resin positions on the Resin manifold using methanol or another •
suitable solvent to remove any residual resin.
Check the level in the waste container and empty if necessary.•
Ensure the ber optic probe is fully inserted into the thermowell on the reaction •
vessel.
Weekly Maintenance
Replace the three • inline lters (PN 172105-M):
• F1 and F2 lters (front of Liberty)
• F3 (reaction vessel drain line)
Biweekly Maintenance
Replace • dip tube lters (PN 167485-M):
Amino acid bottles and external amino acid bottles•
Activator, activator base, deprotection, capping (if used), cleavage (if used) •
bottles
Wash solvent bottles (Main Wash/DMF, Secondary Wash/DCM)•
•
Backush all positions except Main Wash/DMF and Secondary Wash/DCM. (See
Performing a Backush, p. 66, for details.)
Monthly Maintenance
Perform a • sensor calibration on all sensors. (See Performing a Sensor
Calibration, p. 76, for details.)
Perform a• Volume Calibration for all additions except TFA. (See Performing a
Volume Calibration, p. 70, for details.)