Orphee mythic 22 - Page 45

REF : M22/UM/EN/014
3. INSTRUMENT SET UP
MYTHIC 22
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Parameter Specimen
Occurrence
Possible Indication of Error on MYTHIC 22
action
LYM
(# & %)
Nucleated RBC
Erythroblastosis
(+)
Indication: NRBC may be detected on the WBC
scattergram with N1 &/or N2 &/or L1 &/or HL
flags.
Seek for NRBC on smear.
Platelet aggregation
(+)
Indication: aggregates may be detected on the
WBC scattergram with N1 &/or N2 &/or L1 flags.
Seek for platelet
aggregates on smear.
MON
(# & %)
Large or atypical
lymphocytes
(+)
Cause: These lymphocytes are larger than normal
lymphocytes and tend to overlap the MON clump on
the scattergram.
Indication:
reduced LYM/MON gap with LYM band
RL flags.
Seek for erythroblasts on
smear.
Small Neutrophils (+)
Cause : These few segmented and granulations-
lacking Neutrophils tend to overlap the MON clump
on the scattergram.
Indication: reduced NEU/MON gap with NL flags.
Lymphoid & myeloid
Blasts
(+)
Cause : Blasts are large and polymorphic immature
cells that may overlap all normal cells clumps.
Indication
: reduced/absent LYM/MON even
MON/NEU/LYM gap with overlapping population RL
&/or NL &/or HL flags.
Seek for blasts on smear.
Excessive number of
basophils
(+)
Cause: in case of basophilia the basophils clump may
overlap the MON clump on the scattergram.
Indication: reduced LYM/MON gap RL &/or HL &/or
NL flags.
Seek for basophils on
smear.
Immature monocytes (+)
Cause: Immature monocytic line cells proliferate in
certain pathologies (multiple myeloma, monocytic
leukemia) and generate a band at the right of
normal MON clump that causes an inaccurate high
level of monocytes..
Indication : : diffuse MON clump with right-end
flame population IC &/or L5 &/or NL flags.
Seek for immature
monocytes on smear.
NEU
(# & %)
Excessive number of
eosinophils
(+)
Cause: The excessive presence of eosinophils
(eosinophilia) may interfere with NEU counting.
Indication: EOS clump is overlapping NEU clump NH
flag.
check the eosinophils clump
on the scattergram to
eliminate eosinophilia.
Immature
granulocytes
(+)
Cause : metamyelocytes, myelocytes, promyelocytes,
blasts or plasma cells are
large and polymorphous
cells that may overlap NEU clump.
Indication:
diffuse spreading out NEU clump NL
&/or RL &/or IC &/or L5 flags.
Seek for immature cells on
smear.
(+): Instrument count is affected by an increase in the result.
(-): Instrument count is affected by a decrease in the result.
(?): Instrument count is affected by either an increase or decrease in the result which is sample dependent.