Copyright© Orphée SA. All Rights Reserved.
Parameter Specimen
Occurrence
Possible Indication of Error on MYTHIC 22
action
EOS
(# & %)
Granulations
modifications
(-)
Cause:
Toxic or abnormal granules, as much as
degranulated areas may alter optical properties of
eosinophils and cause an erroneous EOS counting.
Indication:
diffuse downwards spreading EOS clump
overlapping NEU clump, NH Flag.
Seek for granulations
modifications on smear.
Atypical
Neutrophils
(+)
Cause:
hyper-segmented or giant Neutrophils may
overlap EOS clump.
Indication:
upwards spreading NEU clump
overlapping EOS clump, NH &/or IC &/or L5 Flags.
Seek atypical neutrophils on
smear.
BAS
(# & %)
Blasts, immature,
atypical cells
(+)
Cause:
abnormal cells may overlap the basophils
clump and interfere with the basophil counting.
Indication:
absence of LYM/MON(NEU) gap with RL
Seek for blasts on smear.
RBC Cold Agglutinin
(-)
Cause:
high IgM level may lower RBC and increase
MCV.
↑
↓
Seek for red cell clumping
on smear.
Severe Microcytosis
(-)
Cause:
in very rare case of severe microcytosis, size
of microcytes
may fall below the minimum RBC
threshold.
↓
↑
Seek for microcytes on
smear.
Macrocytosis (-)
Cause:
in case of macrocytosis, size of macrocytes
may overcome the maximum RBC counting zone.
↓
↑
RBC agglutination (?)
Cause:
agglutinated RBC may cause a low inaccurate
RBC count.
Indication
: abnormal MCH and MCHC values.
Seek for clumped RBC on
smear.
Fragmented RBC
(-)
Cause:
RBC fragments (schizocytes) may agglutinate
and interfere with RBC counting.
↓
↑
↑
Seek for schizocytes on
smear.
Leukocytosis (+)
Cause:
high level of WBC may cause an erroneous
RBC count.
Indication:
very high WBC (>100,000/µL),
↑
, ↑
Centrifuge the sample and
re-assay the re-diluted RBC
part.
(+): Instrument count is affected by an increase in the result.
(-): Instrument count is affected by a decrease in the result.
(?): Instrument count is affected by either an increase or decrease in the result which is sample dependent.
To Next Page
Loading...