Roche Cedex HiRes

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Cedex HiRes Analyzer Operator’s Guide

Software Version 2.2.1

May 2011

For life science research only.

Not for use in diagnostic procedures.

Main Page

Table of Contents9
Contact Addresses15
Prologue15
Revision History15
Copyrights16
Declaration of Conformity16
Intended Use16
- VIII. Software License Agreement17
Trademarks16
Warranty16
Contents of this Operator's Guide20
Conventions Used in this Guide20
Preamble20
FCC Notiﬁ Cation21
- XIII. Warnings and Precautions22
XIV. Disposal of the Analyzer23
A Overview25
Description of the Cedex Hires System26
The Measurement Procedure27
Data Analysis28
Technical Speciﬁ Cations of the Analyzer29
B System Description31
Installing the Cedex Hires System31
Choosing a Suitable Location32
- Connecting or Disconnecting the Device32
Connecting Hardware Components33
- Completing the Windows Mini-Setup33
Installing Cedex Hires Software 2.2 or Updating to Cedex Hires Software 2.234
- Installing the Cedex Hires Software 2.234
  - Setting the Cedex Server to Autostart38
- Starting up the Software39
- Updating Older Cedex Hires Software Version 2.X to Cedex Hires Software 2.240
Starting the Cedex Hires System after Installation45
Securing Access Rights46
- Access Control at the Windows Operating System Level46
- Access Control at the Cedex Hires System Software Level46
C Operation47
Overview of the Cedex Control Center47
- Menu Bar47
- System Menu47
- Measurement Menu48
- Functions Menu48
- Reports Menu49
- Master Data Menu49
- Setup Menu49
- Help Menu50
- Shortcut Area50
- Tracking of Status of Events Carried out by the Analyzer50
Preparing the Analyzer for Measurements51
- Switching on51
- Logging in at the Computer Operating System Level51
- Starting the Cedex Hires Software 2.251
- Performing a HW Startup and Prime52
- Preparing the Reagent Kit53
  - Installing or Changing the Reagent Kit53
  - Reﬁ Lling Containers Individually54
- Checking the Analyzer55
Carrying out a Single Measurement56
- Opening the Measurement Window and Specifying the Operating Mode and Sample Data57
- Deﬁ Ning the Measurement and Analysis (Process) Parameters58
- Preparing the Sample and Attaching It to the Multi Sample Tray or Sample Port59
  - Starting the Measurement59
  - End of Measurement60
- Interrupting a Measurement61
Working with the Multi Sampler62
- The Multi Sampler Defaultcup63
- Preparing the Measurement64
- Carrying out Measurements with the Multi Sampler65
- Interrupting a Multi Run69
- Disruption of Measurements69
- Results70
  - The Multi Run Result List70
Switching off the Cedex Hires Analyzer71
- Carrying out an LM Shutdown and HW Shutdown71
- Logging out72
- Shutting down the Control Center72
  - Software73
Using the Measurement Results Window73
- Result Data Area74
- Sample Parameters and Processing Parameters Areas75
- Image Area76
Using the Measurement List80
- Viewing Analysis Results81
- Searching for Measurements81
Editing Existing Analysis Results/Data Sets82
- The Reprocess Button82
- Effective Data Sets83
Graphical Display of the Analysis Results84
- Enlarging the Histograms84
- Aggregate Histogram85
- Cell Diameter Histogram87
- Object Diameter Histogram88
- Deﬁ Ning Diameter Intervals in the Diameter Histograms88
- Compactness Histogram89
- Measurement Statistics Histogram90
Cultivation Time Chart91
- Creating a CTC View91
- Creating a Cultivation Time Chart95
General Functions of the System99
- Data Management99
  - Printing Reports99
  - Export to Fi Le100
- Data Exchange101
  - Export101
  - Import102
- Viewing and Evaluating the Audit Trail File102
- User Preferences103
- Changing Own Password105
Administrator Functions106
- Administration of User Accounts106
- Password Management110
  - Specifying Password Characteristics110
  - Assigning New Passwords111
- Assigning Work Areas111
- The System Options112
- Adjustment of the Image Analysis Using the Live Operator116
- Archiving Data125
Cleaning and Maintenance Check List127
E Maintenance and Care127
Scheduling Automatic Cleaning Routines128
Daily and Manual Maintenance and Cleaning Routines129
- Checking the Reagent Containers When Manually Reﬁ Lling129
- Cleaning Routines Carried out by the Liquid Management130
- Scanning the Chamber to Verify the Effectiveness of Cleaning Routines132
Automatic Adjustment and Alignment Veriﬁ Cation134
Syringe Maintenance136
- Removing the Syringe136
- Assembling and Installing the Syringe137
- Maintenance of the Syringe Guide and Spindle138
Maintenance of the Flow Chamber, 8-Way Valve and the Remaining Hardware Components139
Operational Data139
The System Suitability Test (SST)140
- Creating SST Checkpoints140
- Performing an SST143
  - Performing an SST with Measurements143
  - Performing an SST Without Measurements144
- Tracking Trends in SST Results over Time145
  - Tracking Trends in SST Checkpoints with Measurements145
  - Tracking SST Checkpoints Without Measurements147
- Locking - Unlocking the System148
Diagnosis of the Cedex Hires Analyzer149
F Troubleshooting149
The System Audit Trail File150
Trace and Logging150
G Appendix151
System Options und User Preferences151

Roche Cedex HiRes - Page 7

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