SYSMEX pocH-100i - 1.2.2. System Limitations and Interferences

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1.2.2. System limitations – Interferences
The abnormal sample conditions listed
here are known to affect test results.
The majority of the listed sample condi-
tionsarenotmeasuredquantitatively
because these conditions vary due to
patient population, patient diagnosis,
age, medications, etc. Customers can
perform studies in order to show how
their specific patient populations are af-
fected by various conditions.
Note
Cause Potential Detection
WBC: false high leukocyte count
Lyse resistant erythrocytes Abnormal WBC histogram (WL flag)
Cold agglutinins /
cryoglobulins Increased MCV, increased MCHC due to decreased HCT and RBC
Platelet aggregation Abnormal WBC histogram (WL flag) and Abnormal PLT histogram (PU flag)
Nucleated erythrocytes Abnormal WBC histogram (WL flag)
RBC: false low erythrocyte count
Cold agglutinins Increased MCV, increased MCHC due to decreased HCT
Microcytosis (severe) Low MCV
Fragmented erythrocytes Abnormal RBC histogram (RL flag) and Abnormal PLT histogram (PU flag)
HGB: false high haemoglobin measure-
ment
Lipaemia MCHC > 36.5 g/dL in severe cases
Abnormal protein MCHC > 36.5 g/dL in severe cases
Leukocytosis WBC >100,000/μL
HCT: false low haematocrit measurement
Cold agglutinins Increased MCV and increased MCHC
Fragmented erythrocytes Abnormal RBC histogram (RL flag) and abnormal PLT histogram (PU flag)
HCT: false high haematocrit measurement Leukocytosis Very high leukocyte count with low erythrocyte count present
PLT: false low platelet count
Platelet aggregation Abnormal PLT histogram (PU flag)
Giant platelets Abnormal PLT histogram (PU flag)
PLT: false high platelet count
Microcytic erythrocytes Low MCV
Fragmented erythrocytes Abnormal RBC histogram (RL flag) and abnormal PLT histogram (PU flag)
Carry-over
WBC 3% or less
RBC 1.5% or less
HGB 1.5% or less
HCT 1.5% or less
PLT 5% or less
Consumables
Reagents: pocH-pack 65/pocH-pack 65XL
Detergent: CELLCLEAN
Controlmaterial:EIGHTCHECK-3WP
Aspirated sample volume
in whole blood mode: approx. 15 μL
inpre-dilutedmode: approx.200μLofthedilutedsample;aminimumof20μLcapillarybloodisrequired.
Number of analyses that can be per-
formed with 1 pocH-pack 65/pocH-pack
65XL
pocH-pack 65: Approximately 65
pocH-pack 65XL: Approximately 240
(These numbers are cycle counts.)
INTRODUCTION
SYSTEM OVERVIEW, TECHNICAL INFORMATION & SETUP
pocH-100
i
Revised February 2011