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Biodex Medical Systems, Inc. © 2016 121
Tec-Control Paper Chromatography procedures are used to perform paper chromatography
tests on kits to ensure the radiochemical purity of labeled radiopharmaceuticals.
1. Select the appropriate detector and Zero Background.
2. From the Nuclear Pharmacy screen, touch <Chromatography>. The Tec-Control Paper Chro-
matography screen is now displayed.
3. Touch <Select Kit Number>. The Inventory Kit List is now displayed. (If there is no existing
kit number for the material to be tested, we suggest cancelling (touch Back) and proceed to
cancel the Nuclear Pharmacy screen to create a new kit.) You can press <Select Kit>, select
the isotope and kit, and then proceed with the chromatography.
NOTE: If the kit is not in the Inventory you can select <Select Isotope> and then select the
Isotope and Kit Type.
4. Touch to highlight the sample kit on which the Tec-Control test will be performed. Touch
<Enter> to advance to the Tec-Control Paper Chromatography screen.
5. Prepare and cut the strips as per manufacturer’s instructions. Place each strip section into a
test tube.
6. Touch to highlight strip #1, or appropriate strip section, and a live reading is displayed in
red.
7. Allow the reading to settle, then touch <Record Reading> to keep the reading for strip #1.
strip #2 is now automatically highlighted.
8. Measure each additional strip and record the readings. Strips do not have to be measured in
order. If the test is for a single strip, skip to step 9.
NOTE: It is important to input the correct formula selection for the type of kit and strips to
be used. Certain kits use one strip, others use two strips. Each strip is cut and the two
sections are counted separately. Different formulas are used depending on the kit selected.
NOTE: A minimum activity of 30 µCi on the strip is required to count a strip section in the
dose calibrator.
NOTE: See Appendix K for formulas used in the calculation.
NOTE: When using a dose calibrator for Tec-Control, the high activity section of a strip
should have an activity of at least 100 µCi for counting. When the count rate is less, use a
Sodium Iodide detector.
9. Touch <Perform Calculations>. Depending on the kit used, the activity for the strip sections
counted are displayed along with the appropriate calculated percentages for:
• % free Tc-99m Pertechnetate
• % Hydrolyzed Reduced Tc-99m
• % Bound Radiopharmaceutical
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