2D-LC User Guide 371
14 Theoretical Background
2D as detector
2
D as detector
Functionally the
2
D of 2D-LC operates like a chemically sensitive detector for the
peaks that elute from the
1
D column. Thus, 2D-LC may be understood as a three
step process:
•
1
D separation (1)
• Sampling of the
1
D (2)
•
2
D separation and detection (3)
Figure 174 Diagram of instrumentation for 2D-LC
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