10 Troubleshooting and Diagnostics
The Basic Principle of Troubleshooting
2D-LC User Guide 294
The Basic Principle of Troubleshooting
Troubleshooting key Concept – Divide and Conquer
The following troubleshooting concept, shows exemplarily how to approach
problems in 2D-LC chromatography.
Most of the following explanations can also be used to isolate and detect
standard LC issues.
The basic principle of troubleshooting should always be a step by step approach
to the 2D-LC problem. As a first step, find out whether the cause of the error is
either:
• The application method, or
• The 2D-LC instrument
For a recommended approach to isolate the cause of the issue, see the graphic
below. All examples use symbols as described in the following table.
Table 35 Description for symbols as used in troubleshooting decision trees
Symbol Description
Shows and describes a problem in the 2D-LC
system. Indicates the starting point for a series
of actions and decisions leading to a solution for
the problem.
Illustrates, that the user must identify what an
observation means. Then the user must take a
decision, which further way of troubleshooting to
follow.
Shows, the user must act to proceed and come
to the next decision or solution.
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