2 Concepts of 2D-LC
Active Solvent Modulation (ASM)
2D-LC User Guide 38
Figure 20 Operating principle with sample loop and ASM capillary in parallel flow path
This is how the same flow path looks inside the 2D-LC valve ASM. The flow
coming from the
2
D pump splits up at valve port 10. One part goes through the
sample loop in deck A and carries parked sample cuts and
1
D solvent. The other
part of
2
D solvent goes through the ASM capillary between valve ports 9 and 6.
Flows unite at port 5 and
1
D solvent is diluted before it arrives at the
2
D column
head.