Troubleshoot
July 29, 2013, 715003794 Rev. B 255
Sample management system troubleshooting
The following table provides troubleshooting suggestions for resolving sample
management system problems in the separations module.
Erratic
flow/pressure
pulsations
Gas dissolved in mobile
phase
Degas solvents.
Air bubble in head Prime solvent
management system to
remove bubble. Increase
the degassing time before
use. Set the bubble detect
alarm in the Mobile Phase
screen (see “Set Mobile
Phase screen parameter
values” on page 151).
Dirty inlet check valves Loosen the check valve for
a few strokes and see if it
starts flowing properly.
You can also try cleaning
the check valves by
running wet prime. To
replace inlet check valves
(see “Replace an inlet
check valve cartridge” on
page 194).
Prime/vent valve open or
leaking
Close or rebuild
prime/vent valve.
Plugged solvent reservoir
diffuser
Clean or replace diffuser.
Plunger seal leaking Make sure that seal wash
is primed and operating
properly. Replace plunger
seal assembly (see “Notes
on replacing the plunger
seals” on page 187).
Solvent management system troubleshooting: (Continued)
Symptom Possible cause Corrective action
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