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Waters Alliance e2695 - Solvent Miscibility

Waters Alliance e2695
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Solvent miscibility
July 29, 2013, 715003794 Rev. B 297
Solvent miscibility
Before you change solvents, refer to the following table to determine the
miscibility of the solvents to be used. When you change solvents, be aware of
these issues:
Changes involving two miscible solvents are made directly. Changes
involving two solvents that are not totally miscible (for example, from
chloroform to water), require an intermediate solvent (such as
methanol).
LiOH Tetramethylammonium hydroxide
pentahydrate
Organic solvents for use with the separations module:
Organic solvents:
4-cyanophenol Chloroform Ethylene glycol Methylene
chloride
Acetone Cyclohexane Formaldehyde n-Propanol
Acetonitrile Cyclohexanone Heptane Phenol
Amyl acetate Dibutyl
phathalate
Hexane Tetrahydrofuran
(THF)
Benzaldehyde Dimethyl
formamide
iso-Octane Toluene
Benzene Dimethyl
sulfoxide
iso-Propanol Waters PIC™
Reagents
Benzyl alcohol Ethanol Lysine
hydrochloride
Xylene
Butanol Ethyl acetate Methanol
Carbon
tetrachloride
Ethylene
dichloride
Methyl ethyl
ketone
Bases for use with the separations module: (Continued)
Bases:

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