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Hamilton Microlab STAR - Ml Star IVD; Total Aspiration and Dispense Monitoring (TADM)

Hamilton Microlab STAR
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Microlab
®
STAR Service Manual
2-4
2.1.2 ML STAR IVD
The Microlab STAR IVD is foreseen to be used in an in vitro diagnostic environment,
e.g. for blood analyses and DNA analytics.
Typical applications are:
Sample preparation for ELISA, LIA, RIA, FIA, agglutination and CLIA tests
Preparation for amplification techniques for DNA detection
Sample archiving and pooling.
2.1.2.1 Total Aspiration and Dispense Monitoring (TADM)
The Microlab STAR IVD is equipped with an additional safety feature, the pressure
based Total Aspiration and Dispense Monitoring (TADM), allowing the in process
control of aspiration and dispense steps. The principle works as follows: Before tip
pickup, the environmental absolute pressure is measured and used as zero base
line. When the liquid level is found, the relative pressure of the air volume within the
tip is measured every 10 ms during the following aspiration and dispensing. The
measurement values are checked on-line if they are lying within a liquid- and
volume-specific, predefined tolerance band. If not, the step is stopped with an error
message. The TADM enables the detection of leaky or clogged tips, blood clots and
foam.

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